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成楚
作者:   来源:   发布时间:2024年09月02日 16:19  点击数:



个人信息:

姓名:成楚

性别:女

职称:讲师

毕业院校:东南大学

专业:生物医学工程

研究方向:疾病早期诊断、靶向药系统构建、生物信息技术

邮箱:chengchu@whpu.edu.cn

科研项目:

1. 安徽省重点研究与开发计划,2023i11020009生物标记物—系列荧光标记修饰核苷酸产品研发与产业化,2023-08-012025-12-31,在研,参与;

2. 国家自然科学基金面上项目,61971123新型两核苷酸合成测序技术及其应用研究, 2020- 01-01 2023-12-31, 结题, 参与

3. 国家自然科学基金面上项目,31970817细胞极性蛋Miranda通过控制Prospero的阈值性分布精确调控肠道干细胞数目的分子机制研究, 2020-01-01 2023-12-31,结题, 参与

4. 国家农业部948”项目,2014-Z27。产丁酸菌及发酵工艺关键技术引进与消化,2014-012015-12,结题,参与。

论文成果:

1. Chu Cheng and Pengfeng Xiao*. Evaluation of the correctable decoding sequencing as a new powerful strategy for DNA sequencing. Life Science Alliance, 2022, 5: e202101294.

2. Chu Cheng, Zhongjie Fei, Pengfeng Xiao*, Huan Huang*, Guohua Zhou*, and Zuhong Lu. Analysis for mutational genotyping using correctable decoding sequencing with superior specificity. Analyst, 2023, 148 (2): 402-411.

3. Chu Cheng, Zhongjie Fei, and Pengfeng Xiao*. Methods to improve the accuracy of next-generation sequencing. Frontiers in Bioengineering and Biotechnology, 2023, 11: 982111.

4. Chu Cheng, Xingyue Gu, Zhongjie Fei, and Pengfeng Xiao*. An Algorithm-optimized Scheme for In-situ Synthesis of DNA Microarrays. Combinatorial Chemistry & High Throughput Screening, 2023, 26: 1609-1617.

5. Chu Cheng*, Qingzhou Cheng, Wei Zhou, Yulong Chen, Pengfeng Xiao. Highly accurate single-color fluorogenic DNA decoding sequencing for mutational genotyping. Journal of Pharmaceutical and Biomedical Analysis, under review.

6. Chu Cheng*, Qingzhou Cheng, Wei Zhou, Yulong Chen, Zhiling Zhang, Jingsi Ye, Pengfeng Xiao. A correctable decoding sequencing enables high accuracy with high throughput. Analytical methods, under review.

7. Zhongjie Fei, Chu Cheng, Rongbin Wei, Guolei Tan, and Pengfeng Xiao*. Reversible superhydrophobicity unyielding magnetic beads of flipping-triggered (SYMBOL) regulate the binding and unbinding of nucleic acids for ultra-sensitive detection. Chemical Engineering Journal, 2022, 431: 133953.

8. Zhiping XiaoChu Cheng, Teng Bao, Lujie Liu, Bin Wang, Wenjing Tao, Xun Pei, Shang-Tian Yang, Minqi Wang*. Production of butyric acid from acid hydrolysate of corn husk in fermentation by Clostridium tyrobutyricum: Kinetics and process economic analysis. Biotechnology for Biofuels, 2018, 11: 164-177.

9. Zhongjie Fei, Ping Liu, Chu Cheng, Rongbin Wei, Pengfeng Xiao* and Youfa Zhang*. Solvent-Responsive Magnetic Beads for Accurate Detection of SARS-CoV-2. ACS applied materials & interfaces, 2023, 15 (4): 4924-4934.

专利成果:

1.肖鹏峰; 成楚. 一种3'端羟基可逆封闭核苷酸合成测序法.中国发明专利:ZL202011152063.0

2.成楚,肖鹏峰. 一种基于核苷酸二聚体为单体的合成测序方法.中国发明专利:CN202211002982.9

3.成楚,肖鹏峰,章志凌,叶静斯. 一种基于标记两类不同核苷酸合成测序方法.中国发明专利:202410615860X

4.董帅,成楚,肖鹏峰.一种基于通用碱基的核酸适配体筛选方法.中国发明专利:2024107780332

5.成楚,赵祥伟,肖鹏峰.DNA微阵列合成优化软件.软件著作权:2023SR0467062

学术交流:

美国俄亥俄州立大学访问学者。